A simple and effective way to solve the entanglement quality of DNA is to "chain" the chain into nanochannels. Conducting advanced research with international schools Trieste participates in research for simulation measurements, and this channel should be able to achieve maximum efficiency.
With the extensive use of DNA analysis and methods of operation, find a way to solve DNA, use channels, or nanochannels, Christian Lettie and Enzo, published in the magazine of the University of Padova, Research.
They said that our idea is to force entry into the DNA channel in order to completely relax it. "But not all channels are possible. According to the diameter of the nanochannel, the wire ends can be arranged in a hook-like structure that will eventually form a knot.
In our study, we used a simulation technique that resulted in a mechanism of the diameter of the channels formed by their junctions, and this nanochannel is a 100-nm wide internal model of the DNA strand. The spontaneous dynamic evolution of this DNA is accompanied by frequent knotting and winding around the ends of the chain.
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